Translational_Unit

Part:BBa_K1202105

Designed by: Muhammed Taha Akcay   Group: iGEM13_ATOMS-Turkiye   (2013-09-24)

TAT-Apoptin: Cancer killing peptide

TAT-Apoptin was designed to induce programmed cell death (apoptosis) in cancer cells, selectively. TAT signal peptide added to direct apoptin into cancer cells.

Apoptin is a novel prospective cancer drug which induces programmed cell death (apoptosis) phase of normal cell life cycle in cancer cells, selectively. The exact mechanism of apoptin is not understood, yet. But, the efficiency and results of the function are researched and pose promising hopeful results for efficient cancer therapy.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal NheI site found at 7
    Illegal NheI site found at 30
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 348
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None